Axis 1

Pathophysiology and therapeutics in myeloproliferative disorders

In addition to academic and industrial clinical trials, the team project includes translational research on:
– mechanisms of resistance to anti-tyrosine kinases
– cellular immunity
– study of minimal residual disease
– the concept of dormant stem cells
– differential expression of genes and the role of small G proteins via BCR-ABL in the phenomena of cell motility and adhesion




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